Tuimoloau (oblique) has been ruled out for the rest of Monday's game against the 49ers.
Tuimoloau suffered an oblique injury early in the second quarter while on coverage on a kickoff. The injury has been deemed by medical staff too severe for the rookie second-rounder to return to Monday's game, so Samson Ebukam and Tyquan Lewis will take on more prominent roles on the defensive line in Tuimoloau's absence.