Driscoll (ankle) will be placed on IR according to head coach Nick Sirianni, Dave Zangaro of NBC Sports Philadelphia reports.
Driscoll had been starting at right guard since returning from his first stint on IR due to a pectoral injury in Week 4. This will be the 24-year-old's second stint on IR, so he will have to miss the rest of the season. Nate Herbig will likely take over starting duties moving forward.