Barkley (hamstring) wasn't spotted at Friday's practice, Jimmy Kempski of PhillyVoice.com reports.
Barkley hasn't practiced the past two weeks and now appears likely to miss a second game. The Eagles will be short-handed, to say the least, with QB Jalen Hurts (blood clot) now joining the long list of starters to miss time this season. If Barkley is indeed inactive, Dameon Pierce will be the favorite to start at running back for Philadelphia.