Barkley (hamstring) has been ruled out for the rest of Sunday's game against the Rams, Zach Berman of The Athletic reports.
Barkley tweaked his hamstring on a six-yard run in the first quarter, and the injury is severe enough for the star running back to be sidelined for the rest of Sunday's game. Tank Bigsby and Will Shipley will handle backfield duties the rest of the way in Barkley's absence.