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Building winning Fantasy football picks requires a full understanding of Fantasy football injuries and Fantasy football matchups. Texans quarterback C.J. Stroud has averaged fewer than 11 Fantasy points over the past six weeks, getting held below 15 points in seven of 12 games overall. However, Fantasy football injuries have played a key role in his disappointing campaign, as wide receivers Nico Collins, Stefon Diggs, Robert Woods and Tank Dell have all missed time. Diggs is the only one who is not healthy heading into the Week 13 NFL schedule, and Stroud has a favorable matchup against a struggling Jacksonville defense.

The Jaguars have allowed a league-high seven games of 20-plus Fantasy points to quarterbacks this season, and three of Stroud's top six Fantasy performances have come against them. Where does this put Stroud in the Week 13 Fantasy football rankings? Before setting your Week 13 Fantasy football lineups, be sure to check out the Week 13 Fantasy football rankings from the proven computer model at SportsLine.

When it comes to ranking players, SportsLine's model beat human experts in Fantasy football for the past several seasons, especially when there were big differences in ranking. Over the course of a season, that could literally be the difference between winning your league or going home empty-handed.

The same model has a proven track record of providing Fantasy football tips, including being ahead of the curve on players like A.J. Brown, Jonathan Taylor, Derrick Henry, Christian McCaffrey, Alvin Kamara, and Jahmyr Gibbs. Anybody who banked on players like those made a run at their league title.

Now, SportsLine has simulated the entire Week 13 NFL schedule 10,000 times and released its latest Week 13 Fantasy football rankings. Head to SportsLine now to see them.

Top Week 13 Fantasy football QB rankings

Here's a look at SportsLine's top Week 13 Fantasy football QB picks: 

1. Joe Burrow, Cincinnati Bengals: Cincinnati is 4-7 but it's been no fault of Burrow's, as he's thrown for 3,028 yards and a league-leading 27 touchdowns with only four interceptions in 11 games. He's had two weeks to prepare for the Steelers and has thrown for 1,035 yards and 12 touchdowns in his last three outings.

2. Josh Allen, Buffalo Bills: Despite losing top receivers Stefon Diggs and Gabriel Davis this offseason, the Bills are 9-2 and Allen is the reason why. He's thrown for 2,543 yards and 18 touchdowns with only five interceptions while also rushing for 316 yards and five scores.

3. Lamar Jackson, Baltimore Ravens: Jackson is coming off a disappointing showing against Pittsburgh, completing 16 of 33 passes for 207 yards, one touchdown and one interception. However, he finished with at least two touchdowns in his previous five games, and he is near the top of the MVP odds heading into Week 13. Jackson has a tricky matchup against the Chargers, but his numbers this season cannot be overlooked.  See more top QBs here.

Top Week 13 Fantasy football RB rankings

Here's a look at SportsLine's top Week 13 Fantasy football RB picks: 

1. Saquon Barkley, Philadelphia Eagles: Barkley rushed for 255 yards and two touchdowns while adding four catches for 47 yards. He's on pace to break Eric Dickerson's single-season rushing record (2,104 yards) and Chris Johnson's single-season scrimmage yards record (2,509). He has reached at least 198 scrimmage yards and two touchdowns in three of his last four games.

2. Christian McCaffrey, San Francisco 49ers: McCaffrey was the rushing champion last year and also led the NFL with 2,023 scrimmage yards and 21 touchdowns. He hasn't been in the end zone yet in three games this season but the 49ers have loaded him up with 56 touches since his return from an Achilles strain.

3. Joe Mixon, Houston Texans: Mixon is yet another veteran running back who seems to have benefitted enormously from a change in scenery this offseason. He's rushed for 786 yards and 10 touchdowns while also adding 23 catches for 226 yards and another touchdown as a receiver over nine games this season. See more top RBs here.

Top Week 13 Fantasy football WR rankings

Here's a look at SportsLine's top Week 13 Fantasy football WR picks: 

1. Ja'Marr Chase, Cincinnat Bengals: Through 11 games, Chase has 73 catches for 1,056 yards and 12 touchdowns. He leads the NFL in the latter two categories and the bye week seems perfectly timed with a tough Steelers defense waiting. He's had 14 catches for 210 yards and a touchdown over his last two meetings with Pittsburgh.

2. Nico Collins, Houston Texans: Despite missing five games with a hamstring injury, Collins is still 13th in the NFL in receiving yards (713) and he had five catches for 92 yards and a touchdown while seeing his snap share rise from 47% to 79% in his second game back. Collins also had long touchdowns called back in both of his games since returning and you can expect the reeling Texans to turn him loose this week against the Jaguars.

3. Puka Nacua, Los Angeles Rams: Nacua has posted back-to-back 100-yard outings to give him three in his six games overall this season. He caught nine of 13 targets for 117 yards against Philadelphia last week, nearly adding another long reception that ultimately drew a pass interference flag in the end zone. Nacua is trending up as much as any wide receiver this week, so the model has him ranked as a top-three player at his position. See more top WRs here.

Top Week 13 Fantasy football TE rankings

Here's a look at SportsLine's top Week 13 Fantasy football TE picks:

1. Taysom Hill, New Orleans Saints: Hill is listed as a tight end but his utility is rooted in the reality that he lines up as a QB, RB, WR and TE throughout the game. New Orleans is coming off a Week 12 bye and when we last saw Hill, he rushed seven times for 138 yards and three touchdowns while also catching eight passes for 50 yards in a win over the Browns. Expect even more creative ways to get Hill the ball on Sunday against the Rams.

2. George Kittle, San Francisco 49ers: Kittle leads NFL tight ends with eight receiving touchdowns this season and there are only two other tight ends with more than four (Mark Andrews and Tucker Kraft both have six). He's missed two games but still has 49 catches for 642 yards and he's been the most consistent option in the San Francisco offense all season.

3. Trey McBride, Arizona Cardinals: The 25-year-old commanded a massive target share in a loss to Seattle last week, catching 12 of 15 targets for 133 yards. He was the team's lone bright spot, as the next closest teammate was only targeted six times. McBride continues to fly under the radar due to his lack of touchdowns, but his target share makes him an excellent pick this week. See more top TEs here.

Top Week 13 Fantasy football defense rankings 

Here's a look at SportsLine's top three Week 13 Fantasy football D/ST picks:

1. Broncos D/ST: Sean Payton's offense is coming around with Bo Nix jumping into the NFL Offensive Rookie of the Year conversation but it's been the defense that has kept Denver in the playoff picture all season. The Broncos rank third in scoring defense and total defense, and now they'll match up with turnover-prone Jameis Winston in Week 13.

2. Jets D/ST: It's been a trainwreck season for the Jets offensively but the defense still ranks 13th in points allowed and eighth in yards allowed. Now they'll matchup with a Seahawks offense that hasn't scored more than 20 points in over a month and that has been held to under 300 yards of total offense in three of four games.

3. Commanders D/ST: Washington has taken advantage of favorable matchups this season, averaging 8.6 Fantasy points against the league's bottom-eight schedule-adjusted offenses. The Commanders are facing a Tennessee offense that ranks No. 25 in the NFL in yards per game (302.1) and No. 28 in points per game (18.4). The Titans have been held under 20 points on eight occasions this season, so the model likes Washington's defense this week. See more top D/ST here

How to get Week 13 Fantasy football rankings

Now that you know who the top three at each position are, you'll want to see the full Week 13 Fantasy football rankings from SportsLine. The model has identified a stunner in the top 10 at tight end, and knowing who it is can give you a huge edge in your league. Head to SportsLine now to get Week 13 Fantasy football rankings

So who should you target in your Week 13 Fantasy football rankings, and which surprising tight end could lead you to victory? Visit SportsLine now to get Week 13 Fantasy Football rankings for every single position, all from the model that has a history of making league-winning calls, and find out.