Brown (knee) has been ruled out for Sunday's game in Denver, John Keim of ESPN.com reports.
With Brown and Curtis Samuel (groin) both out, Cam Sims could be in the mix for a start this week, though he's listed as questionable after missing the past three games with a hamstring injury. The other options to line up alongside Terry McLaurin and slot man Adam Humphries are DeAndre Carter, Dax Milne and Antonio Gandy-Golden.