McLaurin (ankle) was listed as a limited participant on Wednesday's practice estimate, John Keim of ESPN.com reports.
McLaurin has been dealing with an ankle injury since Thanksgiving week, but he's suited up in back-to-back contests on his way to a 9-106-0 line on 15 targets. However, the nadir of his season occurred this past Monday at Pittsburgh, when he was held to two catches (on six targets) for 14 yards. Assuming he can get past the health concern yet again this week, McLaurin will seek a bounce-back effort Sunday in San Francisco.