Toney (hamstring) won't practice Wednesday, Dan Duggan of The Athletic reports.
Kenny Golladay (knee) is also sitting out practice to begin Week 7, leaving his status for Sunday's game against the Jaguars in question. If neither Golladay nor Toney are able to return from multi-game absences this weekend, Darius Slayton, Marcus Johnson, Wan'Dale Robinson, David Sills and Richie James would serve as the Giants' options at receiver.