Savage (quadriceps) has been ruled out ahead of Sunday's matchup with the Browns.
Head coach Doug Pederson told reporters earlier Friday that Savage wasn't expected to suit up for the Jaguars' Week 2 contest, and the team's injury report released later that day confirmed it. Andre Cisco and Daniel Thomas are currently the only two healthy safeties on the Jaguars' active roster, as Andrew Wingard (knee), Tashaun Gipson (suspended) and Savage will all be sidelined Sunday.