The Jaguars designated Hamilton (back) for a return from injured reserve Thursday, Mia O'Brien of 1010 XL 92.5 FM Jacksonville reports.
Hamilton's 21-day practice window thus begins. The Jaguars can activate him from IR at any point within that period, meaning he could have a chance to suit up for Sunday's game against the Colts. The 26-year-old nose tackle should provide Jacksonville's defense with a notable boost when and if he's fully cleared.