McCray was ruled out for Sunday's game against the Bills due to a hamstring injury, Phillip Heilman of The Florida Times-Union reports.
McCray missed Week 10 with a hamstring injury but played in last Sunday's loss to the Steelers, and it remains unclear if he aggravated that injury or is dealing with a new issue. The 28-year-old hasn't topped 20 defensive snaps in a game since Week 1, so the Jaguars defense should be fine without him in Buffalo.