The Jaguars placed Mekari (back) on injured reserve with a designation to return Sunday.
Mekari will be required to miss at least the first four games of the regular season, meaning Week 5 against the Eagles on Sunday, Oct. 11 is the earliest he can play. The California product is recovering from back surgery that he underwent in mid-August. Ezra Cleveland is in line to start at right guard for as long as Mekari is out of action.