Powell (ankle/illness) has been ruled out for Thursday's contest against the Ravens, Mike Garafolo of NFL Network reports.
Powell missed a trio of practices this week, so it doesn't come as a surprise that he won't be available. With Ty Montgomery (foot/hip) also listed as questionable, Josh Adams could step into the No. 2 role in New York's backfield behind Le'Veon Bell, who is slated to return to action after missing the Week 14 win over the Dolphins with an illness.