Coach Robert Saleh said it's "not looking good" for Berrios (quadriceps) to play Sunday against the Bills, Connor Hughes of The Athletic reports.
Berrios was unable to practice Wednesday and Thursday due to the quadriceps issue, and it appears his outlook hasn't improved Friday. The 26-year-old had his best game of the season Week 17 against the Buccaneers with eight catches for 65 yards and a touchdown plus 12 rushing yards and another touchdown, but it appears that will be his final game of the 2021 campaign.