Cooper sustained an ankle injury in the first quarter of Sunday's game against the Titans and is questionable to return.
Per Zack Rosenblatt of The Athletic, the rookie first-round pick opened the game as the Jets' starting slot receiver and made an instant impact on the first drive, breaking free for a 30-yard catch and run that set up a Kenyon Sadiq touchdown run. Cooper may have tweaked his ankle on that play, however, as his availability for the remainder of Week 1 is now in question.