McDonald recorded four solo tackles and three sacks in Sunday's 24-17 win over the Titans.
McDonald lived in Tennessee's backfield, getting to quarterback Will Levis three times to match his combined sack total from the first 16 games of his career. Jermaine Johnson (Achilles) is feared to have suffered a torn Achilles in the victory, and with Haason Reddick holding out, McDonald will likely move into a starting role at defensive end beginning with the Jets' Thursday night game versus the Patriots in Week 3.