Reynolds (back) was listed as a non-participant on Monday's estimated injury report, Tim Twentyman of the Lions' official site reports.
The 27-year-old wideout practiced in a limited fashion last Thursday before ultimately being ruled out for a third straight game due to a back injury. He'll have two more opportunities to practice before the team needs to make a decision on his status for Thursday's matchup against Buffalo, but Reynolds may be trending toward a fourth straight absence.