The Titans waived Edwards on Wednesday, Jim Wyatt of the team's official site reports.
The 28-year-old signed with the Titans on Nov. 6 following his release from the Bills, but he was inactive for Tennessee's loss to the Chargers in Week 10 and has now been cut loose again. Before his brief run in Tennessee, Edwards had played just seven defensive snaps and recorded one total tackle in three appearances with Buffalo this season.