Guion has been suspended for the first four games of the 2017 season after violating the league's policy on performance-enhancing substances, Ian Rapoport of NFL Network reports.
It will be Guion's second suspension in three seasons, as he missed the first three games of the 2015 season due to an offseason arrest. The 29-year-old is slated to be the starting nose tackle for the upcoming season, but the Packers now may target a lineman through the draft or free agency to bolster the defensive line depth. Last season, Guion recorded 30 tackles and one pass defensed in 15 games.