Willis will start in place of QB Jordan Love (knee) with the latter inactive for Sunday's game versus the Colts, Mike Spofford of the Packers' official site reports.
At least for Week 2, this was the likeliest outcome for Green Bay's quarterback room after Love suffered a sprained MCL in his left knee in the season-opening loss to the Eagles in Brazil. Based on a report from Ian Rapoport of NFL Network earlier Sunday, Love is targeting a return to action Week 5 on the road against the Rams, which would give Willis two more starts in addition to Sunday's nod, while Sean Clifford backs him up. In 12 career appearances (three starts), Willis has completed 35 of 67 passes for 350 yards, no touchdowns and three interceptions, rushed 32 times for 144 yards and one touchdown and fumbled four times (three lost).