Legette (knee) has been ruled out for Sunday night's game against the Lions, Alex Zietlow of The Charlotte Observer reports.
Legette will miss a second straight game, and with Jalen Coker (quadriceps) listed questionable, the Panthers could be forced to dip even deeper into their wide receiver depth after Brycen Tremayne and John Metchie played heavy snaps in Week 3 against Cleveland.