Brown (knee) has been ruled out for Thursday's game against the Bears.
Brown injured his knee during the fourth quarter of Sunday's 26-19 win over the Jets. He was held out of all three practices during Week 7 prep, and with both Brown and Alijah Vera-Tucker (hamstring) sidelined Thursday, the Patriots will likely turn to Matt Pryor and Walter Rouse to serve as the starting guards against Chicago. Brown will aim to recover enough to return for Week 8 against Miami on Sunday, Nov. 1.