Wallace (ankle) has exited Sunday's game against the 49ers, Doug Kyed of the Boston Herald reports.
Wallace's exit is a further blow to the Patriots' offensive line, especially at left tackle. With Chukwuma Okorafor (undisclosed) now on the exempt/left squad list and Vederian Lowe (knee) out as well, the Patriots will need to turn to Demontrey Jacobs or Zachary Thomas at left tackle.