Keene (knee) was activated off injured reserve Saturday, Mike Reiss of ESPN.com reports.
The 2020 third-round pick will make his return to the field after missing the last five games with a knee injury. Keene has played just 24 offensive snaps in his young career to date, but it's possible the rookie tight end might be pressed into action if Ryan Izzo (hamstring/hand) is unable to play Sunday.