Smith exited Sunday's game against the Broncos after sustaining a right hand injury.
With Smith headed to the locker room, per Mike Garafolo of NFL Network, Kenny Pickett is in at QB for the Raiders. Aidan O'Connell was designated the team's emergency No 3 QB on Sunday. Prior to his departure, Smith completed 13 of his 21 pass attempts for 116 yards and a TD and carried once for four yards.