Powell didn't practice Wednesday due to an illness and is listed as questionable for Thursday's matchup against Las Vegas, Anthony Galaviz of The Fresno Bee reports.
Along with Powell, fellow wideout Lance McCutcheon (shoulder) is also listed as questionable, so the Rams' passing attack could be further depleted against Las Vegas if neither gains clearance ahead of the 8:15 p.m. ET kickoff. Powell has played north of 40 percent of the Rams' offensive snaps in both of the past two weeks, carrying three times for 45 yards and adding six receptions for 45 yards on six targets.