Hopkins was placed on the reserve/COVID-19 list Tuesday due to a positive test of the virus.
The tight end will enter the league's COVID-19 protocols, but since he's vaccinated, he'll be able to play Sunday against the Seahawks if he's asymptomatic for 48 hours and is able to produce two consecutive negative COVID-19 tests. Hopkins has appeared in three straight games for the Rams, logging 33 offensive snaps without a target.