Keenum completed 5 of 9 passes for 32 yards in Thursday's 24-3 loss to the Seahawks.
Keenum made his first appearance since Week 10 in relief of Jared Goff, who exited the game late in the fourth quarter to be evaluated for a concussion. The 28-year-old, who started the first nine games of the season, would presumably suit up against the Rams in Week 16 if Goff was unable to return in time.