Coach Sean McVay said Friday "the hope" is Williams (hamstring) will be ready to come off IR and play Week 5, Sarah Barshop of ESPN.com reports.
Williams will need to spend at least four games on IR while recovering from a hamstring injury he initially sustained in late July. Until Williams is back on the field, however, Cobie Durant will project to handle a starting role at cornerback across from veteran Tre'Davious White, beginning with Sunday night's regular-season opener against the Lions.