Metcalf (knee) won't practice Wednesday, but head coach Mike Macdonald said he's optimistic the wideout will return to practice Thursday and then play in Sunday's game against the Rams, Curtis Crabtree of Fox 13 Seattle reports.
Metcalf didn't practice last week and ended up missing a 31-10 loss to the Bills after suffering an MCL sprain the week before. His sprain isn't thought to be especially, but Macdonald's optimism should probably be taken with a grain of salt, especially with a bye week coming up after Sunday's game and then two more divisional games scheduled on the other side of the bye (Week 11 at San Francisco, Week 12 vs. Arizona).