Claypool (toe) didn't practice Wednesday, Ray Fittipaldo of the Pittsburgh Post-Gazette reports.
Claypool underwent an MRI on Tuesday after injuring his toe during Monday's 29-27 win over the Bears. If he can't make it back for Sunday's game against Detroit, the Steelers will be left with James Washington, Ray-Ray McCloud and Cody White behind go-to receiver Diontae Johnson.