Houston activated Cooks (illness) from the reserve/COVID-19 list Wednesday, Aaron Wilson of Sportstalk 790 Houston reports.
Cooks was spotted on the field at practice earlier Wednesday, which foreshadowed his return from the list. Now that he's officially back on the 53-man roster, Cooks is poised to serve as Houston's No. 1 receiver Sunday against the 49ers. Between his previous two games working with quarterback Davis Mills, Cooks put together a 15-203-2 receiving line on 21 targets.