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Mixon (ankle) is inactive for Sunday's game against the Jaguars.

After missing practice Wednesday and Thursday, Mixon returned to a limited session Friday before being deemed questionable heading into the weekend. With Mixon officially inactive for the second straight contest and Dameon Pierce (hamstring) also still out, Cam Akers -- who started in place of Mixon in Week 3 -- is in line to continue to see an expanded role in Houston's backfield versus Jacksonville, with Dare Ogunbowale, British Brooks and J.J. Taylor available to handle complementary backfield touches. Mixon will target a potential return to action Oct. 6 against the Bills.

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