Siemian agreed to a contract with the Titans on Wednesday, Turron Davenport of ESPN.com reports.
In a corresponding move, the team waived seventh-round pick Cole McDonald, who had been penciled in as the team's No. 3 signal-caller behind Ryan Tannehill and Logan Woodside. Siemian, a seventh-round pick himself (in 2015), gives the Titans a quarterback with prior NFL starting experience behind Tannehill, who signed a long-term extension in March.