Spears (knee) is active for Sunday's game against the Colts.
Spears drew the questionable tag for Sunday's AFC South showdown after logging a full practice Friday, and the fourth-year running back has been cleared by medical staff to suit up against Indianapolis. He has 17 carries for 65 yards and 14 catches (on 16 targets) for 68 yards through five regular-season games while serving as the Titans' RB2 behind Tony Pollard.