Jefferson (ankle) remained absent from Friday's practice, Kevin Seifert of ESPN.com reports.
Jefferson hasn't practiced at all this week after twisting his ankle seven snaps into last Sunday's game against the Bucs. It's looking likely that Jefferson will now miss Week 4 against Miami. If so, Jordan Addison, Jauan Jennings and Tai Felton should see the bulk of the wideout snaps for the Vikings.