ACC
Start
Darren Evans, RB, Virginia Tech vs. Central Michigan
Filling in for Ryan Williams, Evans rushed 15 times for 160 yards and two scores last week against North Carolina State. Even if Williams can go in this game, expect the Hokies to ease him back into the mix against Central Michigan, making Evans a good start.
Josh Adams, RB, Wake Forest vs. Navy
Adams averaged 5.1 yards per carry last week against Georgia Tech, while doubling his previous season-high in carries with 20. With the Demon Deacon passing game still struggling since the graduation of Riley Skinner, expect a heavy dose of Adams against the Midshipmen.
Sit
Christian Ponder, QB, Florida State at Miami (FL)
The Hurricanes held Kyle Parker to 14-of-33 for 149 yards and forced three interceptions last week. In fact, no opposing quarterback has passed for more than 233 yards or completed more than 53 percent of their passes against them. Combine that with a hostile Miami environment, and Ponder's best spot might be the bench this week for fantasy purposes.
Perry Jones, RB, Virginia at Georgia Tech
Jones received more carries than last week than Keith Payne, who has struggled since his four-touchdown opening game. However, Jones still managed just 28 yards on 11 carries against Florida State. With Georgia Tech playing triple-option ball control, along with a decent defense, Jones may not have much room to roam against the Yellow Jackets.
Big 12
Start
Josh Cooper, WR, Oklahoma State at Louisiana-Lafayette
Brandon Weeden, Kendall Hunter and Justin Blackmon are obvious, but Cooper is the second-leading receiver for the Cowboys and has a 100-yard game already under his belt this season.
Jay Finley, RB Baylor at Texas Tech
The Red Raiders allowed an astounding 251 yards on the ground to Iowa State last week, and Finley is averaging five yards per carry for the Bears. With so much attention needing to be focused on Robert Griffin, Finley could be a sneaky play.
Sit
Baron Batch, RB, Texas Tech vs. Baylor
It looks like it might not take long for Tommy Tuberville's seat to get hot in Lubbock, as the Red Raiders are 2-2 after an embarrassing loss to Iowa State. A big part of that disappointing record is Texas Tech's non-existent running games. After averaging 5.9 yards per carry the past two years, Batch is averaging just 4.07 per rush in 2010.
Austen Arnaud, QB, Iowa State vs. Utah
A non-conference reprieve for Arnaud and the Cyclones? Think again, as the Utes are coming to town. Though Arnaud tossed four touchdowns last week, Utah is allowing just 12.8 points per contest.
Big East
Start
Jock Sanders, WR, West Virginia vs. UNLV
Sanders has been relatively quiet this season, and is even being outdone by fellow receiver Tavon Austin. However, he faces a Rebel squad that isn't built to stop players like Sanders
Zach Collaros, QB, Cincinnati vs. Miami (OH)
Don't forget about Collaros coming off a bye week, as the Bearcat gunslinger has gone for over 300 yards and three touchdowns in each of his last two games. If he can perform against North Carolina State and Oklahoma, the sky's the limit against the RedHawks.
Sit
Dion Lewis, RB, Pittsburgh at Notre Dame
Unfortunately for Lewis, he has been a frequent participant on the “Sit” side this year. Ray Graham got the start last week against Florida International and ran for an insane 277 yards and three scores against the lowly Panthers. However, Graham has outperformed Lewis all year long
Tom Savage, QB, Rutgers vs. Connecticut
Savage is dinged up and hasn't exactly thrived in 2010 either. He's completed just 51.5 percent of his passes while tossing just one touchdown on the year. Three interceptions in that same span means that even if he were healthy, Savage would not be a recommended option. Chas Dodd may start in his place, and he's best left riding the pine as well.
Big Ten
Start
James White, RB, Wisconsin vs. Minnesota
With John Clay hobbled by bad ankles and White gaining chunks of yardage, there is now an open competition for the Badgers' featured back, meaning White could see even more touches. Minnesota also poses little threat to Wisconsin, leaving White as a must- start.
Jeremy Ebert, WR, Northwestern vs. Purdue
Maybe the best receiver that nobody is talking about? Ebert is averaging 18.2 yards per catch and has found the end zone five times on the young season. While Northwestern is a soft 5-0, Purdue is not up to snuff this year, making the Wildcat passing game destined for a superior output.
Sit
Ben Chappell, QB, Indiana at Ohio State
Tough to bench Chappell, as he's been lights out so far for the surprising Hoosiers. However, he hasn't faced a defense quite like OSU's yet.
Junior Hemingway, WR, Michigan vs. Michigan State
Hemingway had a big game against Indiana last week, but it's difficult to imagine him repeating against the Spartans. It's not as if Michigan State's defense is that great, but Hemingway is no better than the third option in the Michigan passing game behind Roy Roundtree and Darryl Stonum.
Conference USA
Start
Joe Banyard, RB, UTEP vs. Rice
Banyard has been productive in the absence of injured star Donald Buckram, rushing for 330 yards and five touchdowns on the year. With Buckram still dinged up and a game against Rice that the Miners should take pretty easily, Banyard could get the majority of the touches out of the backfield for UTEP.
Cole Beasley, WR, SMU vs. Tulsa
Aldrick Robinson is the go-to receiver for Kyle Padron, but Beasley has come on strong in 2010, including an eight catch, 158-yard output against Rice last week. In fact, Beasley actually has more receptions than Robinson. With a shootout expected against the Green Wave, Beasley could figure prominently onto the stat sheet.
Sit
Terrance Broadway, QB, Houston vs. Mississippi State
The redshirt freshman is still learning the offense, and it appears as though a change in philosophy is afoot in deferring to Bryce Beall on the ground. An SEC opponent this week certainly won't help his maturation, and there have even been rumblings that Broadway will be benched.
Jerrell Rhodes, RB, Memphis at Louisville
Rhodes has been splitting carries with Gregory Ray, and Big East foe Louisville figures to stack defenders in the box and force whoever starts at quarterback for the Tigers, either Ryan Williams or Cannon Smith, to beat them through the air.
Independents
Start
Trent Steelman, QB, Army at Tulane
Steelman only produced eight touchdowns in 2009, but he hasn't been so modest in 2010. Through five games he already has nine touchdowns this year, with all of them coming in the past three weeks. Tulane's defense isn't exactly intimidating, so Steelman should keep his scoring streak alive.
Sit
Armando Allen, RB, Notre Dame vs. Pittsburgh
Allen has received at least 13 carries in each of Notre Dame's first five contests, but has failed to notch a 100-yard output. He'll face a Pitt defense that has held three of four opponents to less than three yards per carry.
MAC
Start
Jacquise Terry, RB, Kent State vs. Akron
Terry rushed 23 times for 86 yards and two scores last week, while the Zips are 113th in the nation in points per game allowed at 39.8. Northern Illinois bulldozed Akron to the tune of 228 yards on the ground last week, and as such Terry should get plenty of opportunities to break off a few big gains.
Cory Sykes, RB, Ball State vs. Western Michigan
Sykes missed two games but came back with a vengeance last week to the tune of 13 carries for 92 yards against Central Michigan. Though Eric Williams is still getting about equal carries, Sykes is averaging six yards per rush and is too good to be kept of the field entirely.
Sit
Eric Page, WR, Toledo at Boise State
Page gets one week off due to a matchup on the Smurf Turf with Boise State. The Rockets' leading receiver, Page was held to just 43 yards against Arizona in his season debut, the closest team that Toledo has faced talent-wise to Boise.
Ryan Radcliff, QB, Central Michigan at Virginia Tech
Radcliff has passed for 1,437 yards and seven touchdowns this season, but has also tossed seven interceptions, including five in his last two games. The Hokies appear to be on the upswing, making Radcliff best left to play another day.
MWC
Start
Jereme Brooks, WR, Utah at Iowa State
Brooks had a down game in Utah's rout of San Jose State, but is the leading receiver for the Utes and should be looked to many times in the den of a Big 12 foe. He already has four touchdowns in four games.
J.J. Di Luigi, RB, BYU vs. San Diego State
A freshman quarterback's best friend is the running game, and Di Luigi has been beastly in 2010, averaging a robust 5.8 yards per carry en route to 374 yards and three touchdowns. He also is a superb ball-catcher out of the backfield, leading the Cougs in that category as well. In a down year for BYU, Di Luigi is the lone bright spot.
Sit
Omar Clayton, QB, UNLV at West Virginia
Clayton had just 214 yards, one touchdown and one interception last week against Nevada, and the going only figures to get tougher in a road game against West Virginia. UNLV is a mere 81st in the nation in points scored this season, further diminishing his fantasy prospects.
Alvester Alexander, RB, Wyoming at TCU
Alexander had a 100-yard game against Air Force, but overall has been averaging just 3.1 yards per rush. The TCU defense has been stout, particularly against the run, and Alexander has failed to top 50 yards in four of five contests this season.
Pac-10
Start
Kerry Taylor, WR, Arizona State at Washington
Consistency has been the name of the game for Taylor, as he has hauled in at least four passes and gained at least 66 yards in each of his last four games. The Huskies are allowing 32.5 points per game this season, good for just 99th in the land.
Nic Grigsby, RB, Arizona vs. Oregon State
After being held to just 65 yards last week against Cal, and just 27 the week before against Iowa, look for Grigsby to bounce back against an Oregon State squad that allowed 161 yards on the ground last week to Arizona State.
Sit
Kevin Riley, QB, California vs. UCLA
The Bruins have been hot, including knocking off Texas two weeks ago. UCLA also plays ball control, as they are 10th in the nation in rushing yards. Combine that with a zero-touchdown performance from Riley last week, and Cal's gunslinger might be worth a bench slot this week.
Jeff Tuel, QB, Washington State vs. Oregon
Tuel passed for 311 yards and two scores last week against UCLA, but Oregon will jump to a huge lead quickly, forcing Tuel and the Washington State offense to make ill-advised decisions in a desperate attempt to keep up.
SEC
Start
Larry Smith, QB, Vanderbilt vs. Eastern Michigan
If you're in a bind, look no further than Smith, an SEC quarterback not worth a start in any conference game, but could prove useful against a MAC opponent. Smith had a decent game last week against UConn as well, tossing two touchdowns while rushing for 64 yards.
Ryan Swope, WR, Texas A&M vs. Arkansas
Jeff Fuller deservedly gets all the press as far as Aggie wideouts go, but Swope has quietly led the team in receptions this year. After totaling six catches for 80 yards and a touchdown during last week's shootout against Oklahoma State, Swope is a decent bet to put up similar numbers in what should be another shootout against Arkansas.
Sit
Marcus Lattimore, RB, South Carolina vs. Alabama
You might be forced to start Lattimore regardless of matchup, but the Crimson Tide are No. 1 in the country in points allowed at a paltry nine per contest. The true freshman has some performances in his future, but this week won't be one of them.
Rueben Randle, WR, LSU at Florida
The Gators are going to be fuming after getting shellacked by Alabama on national television. Combine that with an unstable quarterback position for the Tigers, and regardless of whether Jarrett Lee or Jordan Jefferson starts, LSU's leading receiver may not get many productive touches.
Sun Belt
Start
T.Y. Hilton, WR, Florida International vs. Western Kentucky
Besides Western Kentucky running back Bobby Rainey, Hilton will be arguably the most gifted player on the field in this contest. Though his production has sagged mightily since his 2008 freshman campaign, Hilton is still averaging around five grabs per contest, and has a good shot to get going against the Hilltoppers.
Allen Muse, WR, Arkansas State at North Texas
Quietly, Muse has put together a standout season, hauling in 19 passes for 382 yards and three touchdowns. Those outside Sun Belt-only leagues should start to take notice of Muse and his quarterback, Ryan Aplin.
Sit
Frank Goodin, RB, Louisiana-Monroe vs. Florida Atlantic
Goodin is averaging just 2.5 yards per carry and has failed to score a touchdown after an 09-10 campaign in which he rushed for 1,126 yards on 219 carries, while also finding the end zone 13 times. Until he can get back on track, Goodin is too unreliable at this time.
Darius Carey, WR, North Texas vs. Arkansas State
Carey is a quality receiver and has four scores so far in 2010, but the extent of his team's bad luck is unparalleled: the Mean Green are down to their No. 4 quarterback in light of the wrist injury to Riley Dodge, who actually started the year at wide receiver.
WAC
Start
Marcus Allen, WR, New Mexico State vs. New Mexico
The battle for New Mexico rages on in Las Cruces this week, pitting a pair of teams that have yet to get in the win column. While running back Seth Smith may also make a good start, Allen is averaging 19.6 yards per catch and has two touchdowns on the year.
Diondre Borel, QB, Utah State at Louisiana Tech
Borel was a cool 10-for-13 for 192 yards and two total touchdowns against BYU last week, the Aggies' first victory over the Cougars since 1993. Louisiana Tech should not pose as much of a threat, and if Utah State doesn't fall into the trap game, Borel should post some standout figures.
Sit
Jalal Beauchman, WR, San Jose State at Nevada
The leader in receiving yards for the Spartans, Beauchman might be without quarterback Jordan La Secla in this one. And even if La Secla plays, he will be less than 100 percent and facing a ranked Nevada squad.
Chizzy Dimude, RB, Hawaii at Fresno State
The Hawaii spread offense is fantastic for quarterback Bryant Moniz and receivers Greg Salas and Kealoha Pilares, but not so much for the running backs of the Warriors. Dimude has been getting the most touches out of the Hawaii backfield of late, but remains a virtual non-factor with Hawaii passing on nearly every down.