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Jaydon Blue RB | DAL
Cowboys' Jaydon Blue: Bumps up depth chart with Sanders out
Blue will serve as the Cowboys' No. 2 RB behind starter Javonte Williams moving forward after Miles Sanders (knee/ankle) was ruled out for the rest of the season, Jon Machota of The Athletic reports.
Sanders initially hurt his ankle just before halftime of Dallas' Week 4 tie with the Packers and then was listed with knee and ankle injuries ahead of being inactive this past Sunday at the Jets. A limited practice this Wednesday indicates Sanders was making a last-ditch effort to prove his health, but Executive Vice President Stephen Jones said Friday that he'll miss the remainder of the campaign. Blue made his pro debut Week 5 and turned four carries into seven yards on 11 offensive snaps, so he likely will be contained to scraps behind the workhorse that has been Williams for the foreseeable future.
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CeeDee Lamb WR | DAL
Cowboys' CeeDee Lamb: Ruled out for Week 6
Lamb (ankle) has been ruled out for Sunday's game against the Panthers, Clarence Hill Jr. of AllDLLS.com reports.
He still hasn't practice since suffering a high-ankle sprain in a Week 3 loss to the Bears. With Lamb and KaVontae Turpin (foot) both ruled out again, the Cowboys figure to deploy George Pickens, Jalen Tolbert and Ryan Flournoy as their top three wide receivers.
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Miles Sanders RB | DAL
Cowboys' Miles Sanders: Out for the season
Sanders (knee/ankle) will miss the rest of the season, Jon Machota of The Athletic reports.
Cowboys EVP Stephen Jones said the team is "fired up" about what Jaydon Blue can do as the No. 2 running back. The rookie had just seven yards on four touches in the first game Sanders missed, with Javonte Williams again dominating backfield work. In any case, Sanders apparently will be placed on injured reserve soon.
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Mac Jones QB | SF
49ers' Mac Jones: Doing more at practice Friday
Jones (knee/oblique) is practicing Friday and doing more throwing than the day before, Cam Inman of The San Jose Mercury News reports.
It looks like Jones is preparing to start, while Brock Purdy (toe) is doing side work but not quite ready to practice. The 49ers still may leave the door open for Purdy to start if he makes progress this weekend, but the more likely scenario right now is Jones fighting through oblique and knee injuries to make another start this Sunday at Tampa Bay.
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Brandon McManus K | GB
Packers' Brandon McManus: Questionable for Week 6
McManus (right quadriceps) is listed as questionable for Sunday's game versus the Bengals, Wes Hodkiewicz of the Packers' official site reports.
McManus showed up on Green Bay's first Week 6 practice report Wednesday as limited due to a right quad injury, and he maintained that activity level through Friday. During a media session Thursday, he said "I plan on playing" against Cincinnati, but his status now won't be confirmed until about 90 minutes before Sunday's 4:25 p.m. ET kickoff. McManus added that the "tug" he felt in his quad Wednesday "felt very similar to when I had a quad-type deal in 2022," but he ended up taking the rest of that week off and handled placekicking duties on the ensuing Sunday. If there ends up being any doubt about McManus' status from a Packers perspective, the team may elevate Mark McNamee from the practice squad Saturday. If that doesn't occur, though, McManus should be good to go this weekend.
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Darnell Mooney WR | NYG
Falcons' Darnell Mooney: Not practicing Friday
Mooney (hamstring) didn't practice Friday, Marc Raimondi of ESPN.com reports.
Mooney made an early exit Week 4 and still isn't ready to practice after a Week 5 bye. Falcons coach Raheem Morris said the wideout is day-to-day, but there's not much cause for optimism as it pertains to Monday's matchup with Buffalo. Casey Washington played 95 percent of Atlanta's snaps when Mooney was inactive back in Week 1, catching three of six targets for 33 yards in a loss to Tampa Bay.
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Brock Bowers TE | LV
Raiders' Brock Bowers: Not expected to play Sunday
Coach Pete Carroll noted Friday that Bowers (knee) isn't expected to play Sunday against the Titans, Ryan McFadden of ESPN.com reports.
Per Levi Edwards of the Raiders' official site, Carroll indicated that that Bowers "isn't quite ready yet" while acknowledging that the tight end more than likely will be out this weekend. On the plus side for the team, Carroll said that Michael Mayer (concussion) "had a great week" and will be good to go against the Titans.
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Terry McLaurin WR | WAS
Commanders' Terry McLaurin: Listed as non-participant
McLaurin (quadriceps) is listed as a non-participant on Friday's practice report.
Friday's report is an estimate, as the Commanders didn't actually practice. If McLaurin doesn't return to practice Saturday, he'll likely be listed as out/doubtful for Monday's game against Chicago.
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Kyler Murray QB | MIN
Cardinals' Kyler Murray: Questionable for Sunday
Murray (foot) is listed as questionable for Sunday's game at Indianapolis, Tyler Drake of ArizonaSports.com reports.
Murray returned to practice Friday, listed as a limited participant after sitting out the previous two days. He may be a game-day decision ahead of the 1:00 p.m. ET kickoff Sunday, with Jacoby Brissett ready to step in and start after getting most of the first-team reps during practice this week.
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Kalif Raymond WR | CHI
Lions' Kalif Raymond: Questionable for SNF
Raymond (neck) is listed as questionable for Sunday's game against the Chiefs, Justin Rogers of Detroit Football Network reports.
Raymond was limited in practice Thursday and Friday after kicking off Week 6 prep with a DNP. If healthy enough to play Sunday night, Raymond should continue to provide depth at wide receiver while working as Detroit's primary punt returner.