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Dexter Lawrence DT | CIN
Giants' Dexter Lawrence: Questionable to face New Orleans
Lawrence (illness) did not participate in Friday's practice and is listed as questionable for Sunday's game against the Saints.
Lawrence has been under the weather all week, which prevented him participating in practice. The 2019 first-rounder will have the weekend to recover from his illness, but his official status for Sunday's game may not be announced until approximately 90 minutes before the 1:00pm ET kickoff. D.J. Davidson -- who has been cleared to play after nursing a foot injury this past week -- would be in line for a bigger role on the Giants' defensive interior if Lawrence is not cleared to play.
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Deebo Samuel WR | SF
Commanders' Deebo Samuel: Slated to suit up Sunday
Coach Dan Quinn said Friday that Samuel (heel) will play Sunday at the Chargers, Tashan Reed of The Washington Post reports.
Whether or not Samuel enters the weekend with a designation remains to be seen, but after logging work in just one practice during Week 5 prep, the wide receiver is slated to be available Sunday. With Terry McLaurin (quadriceps) and Noah Brown (groin/knee) not making the trip to Los Angeles, Samuel is the sole name option at the position available for Jayden Daniels (knee) in the second-year signal-caller's return to action.
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Jevon Holland SAF | NYG
Giants' Jevon Holland: Cleared to play Week 5
Holland (neck/calf) does not carry an injury designation into Sunday's game against New Orleans.
Holland was limited in practice all week due to calf and neck injuries -- the latter of which he sustained during the Giants' Week 4 win over the Chargers -- but the 2021 second-rounder has progressed enough in his recovery to be cleared to play Sunday. Holland has 23 tackles (13 solo) and one pass defense through the first four games of the regular season.
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Isaac Yiadom CB | WAS
Saints' Isaac Yiadom: Won't play against NYG
Yiadom (hamstring) has been ruled out for Sunday's game against the Giants, Matthew Paras of The New Orleans Times-Picayune reports.
Per Paras, Yiadom sustained a hamstring injury during practice this past week. The injury prevented Yiadom from participating in practice Thursday and Friday, and the 2018 third-rounder will not take the field for Week 5 as a result. Quincy Riley has seen the field on defense in each of the last two games, and he figures to be the top candidate for an increased role in the secondary Sunday in Yiadom's absence. Week 6 against the Patriots on Sunday, Oct. 12 is Yiadom's next opportunity to play.
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Dyami Brown WR | WAS
Jaguars' Dyami Brown: Another limited practice
Brown (shoulder) remained limited at practice Friday.
Brown, who was inactive Week 4, also was limited Thursday, so he'll probably need to practice fully Saturday in order to approach Monday night's game against the Chiefs without an injury designation. If Brown is limited or out for the contest, Parker Washington would be in line to see added snaps alongside fellow WRs Brian Thomas and Travis Hunter.
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Isaiah Davis RB | NYJ
Jets' Isaiah Davis: Moves into No. 2 role
Davis is expected to serve as the Jets' No. 2 running back beginning with Sunday's game against the Cowboys after New York placed Braelon Allen (knee) on injured reserve Friday, Rich Cimini of ESPN.com reports.
Head coach Aaron Glenn noted that Allen is expected to miss an estimated 8-to-12 weeks while recovering from what's believed to be an MCL injury, giving Davis an extended runway as the top backup to starter Breece Hall. Through the first four weeks of the season, Davis had used mostly as a third-down back, playing fewer than 35 percent of the offensive snaps in each contest while totaling 27 yards on five carries and 24 yards on three receptions. The Jets signed Khalil Herbert off the Seahawks' practice squad Thursday to bolster their depth in the backfield while Allen is out, but Davis should get the first chance to serve as the team's lead option if Hall needs to miss time at any point. So long as Hall is healthy, however, Davis likely won't be in store for a big enough boost in playing time and touches sans Allen to make him usable in most fantasy leagues.
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Trey Palmer WR | NO
Saints' Trey Palmer: Ruled out for Week 5
Palmer (ankle) has been ruled out for Sunday's game against the Giants, Matthew Paras of The New Orleans Times-Picayune reports.
Palmer was unable to practice Thursday and Friday due to an ankle injury that is severe enough for him to be sidelined for Sunday's NFC clash. Veteran wide receiver Dante Pettis was signed to the Saints' practice squad Thursday, and he joins Kevin Austin and Tommy Mellott as the top candidates to be elevated to New Orleans' active roster due to Palmer's injury. Palmer's next chance to play is Week 6 against the Patriots on Sunday, Oct. 12.
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Marvin Mims WR | DEN
Broncos' Marvin Mims: Good to go this week
Mims (hip/ankle) doesn't carry an injury designation ahead of Sunday's game against the Eagles, Aric DiLalla of the Broncos' official site reports.
Mims was limited Wednesday and Thursday, but a full session Friday paves the way for the wideout to be available this weekend. On the heels of his most productive game of the season in which he logged six catches on as many targets for 69 yards and one carry for a 16-yard TD in Monday's 28-3 win over the Bengals, the 2023 second-rounder profiles as a hit-or-miss fantasy lineup option Week 5, with fellow WRs Courtland Sutton and Troy Franklin -- who have been out-snapping Mims each week thus far -- both in line to continue to see their share of targets this weekend.
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Greg Dortch WR | BUF
Cardinals' Greg Dortch: Questionable for Sunday
Dortch (collarbone) is listed as questionable for Sunday's contest against the Titans, Zach Gershman of the Cardinals' official site reports.
Dortch managed three consecutive limited practices this week due to a collarbone injury, while fellow WR Zay Jones progressed enough to gain clearance from the concussion protocol. Even if Dortch is active Sunday, he'll likely cede the No. 3 role to Jones after he tallied a 4-35-0 line on five targets last Thursday versus the Seahawks in place of the latter.
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Tommy Tremble TE | CAR
Panthers' Tommy Tremble: Headed for another start
Tremble appears to be in line to serve as the Panthers' top tight end in Sunday's game against the Dolphins while Ja'Tavion Sanders (ankle) remains out.
While Sanders was sidelined for last Sunday's 42-13 loss to the Patriots, Tremble stepped up to play a season-high 75 percent of the Panthers' offensive snaps, finishing with five catches for 42 yards and a touchdown on eight targets. Tremble could be headed for a similar snap share once again in Week 5, though his usage in the passing game may take a hit since the Panthers will get one of their key pass catchers (Xavier Legette) back from a two-game absence due to a hamstring injury.