Hofer will start Tuesday's road game against Chicago, Lou Korac of NHL.com reports.
Hofer will draw his second start in the Blues' first three games of the regular season Tuesday. He posted a shutout during his Opening Night start in Dallas on Friday, turning aside all 25 shots he saw during a 4-0 victory. Across three starts against the Blackhawks last year, Hofer went 2-1-0 with a 4.29 GAA and .859 save percentage.