Markstrom is starting Wednesday's home game against the Blackhawks, Jameson Olive of the Panthers' official site reports.
Markstrom returned to action Monday against the Red Wings and allowed four goals on 28 shots during the 5-3 defeat. He'll draw a second consecutive start and will have a favorable matchup against the Blackhawks, who have logged 2.20 goals per game to begin the regular season, which is the second-worst mark in the NHL.