White Sox manager Robin Ventura said after Saturday's game against the Rays that Hector Santiago will replace Gavin Floyd in the rotation. Floyd will be placed on the 15-day disabled list with a flexor muscle strain in his right elbow.
His first start is scheduled for Friday against the Royals.
Santiago came on for the injured Floyd Saturday night in the third inning and allowed four runs on 10 hits over 3 2/3 innings. The left-hander also struck out four and did not walk a batter.
Santiago has a 2.51 ERA through seven relief appearances. He went 2-0 with a 1.86 ERA in four starts last season.