Dodgers pitcher Clayton Kershaw had a hard time keeping the ball in the park in Wednesday's series finale against the Padres. He allowed five runs (three earned) on seven hits -- including three homers -- over 5 1/3 innings in a 7-2 loss.

It was the worst outing of his career against the division foe.

The left-hander made it through the first three frames scoreless and became the fastest player in franchise history to reach 1,000 career strikeouts when he whiffed Yonder Alonso in the second. But he got tagged with a three-spot in the fourth before surrendering a solo home run to Chris Denorfia in the fifth. Kershaw was pulled after giving up back-to-back hits in the sixth, including a solo bomb to Kyle Blanks.

Kershaw, who threw 109 pitches, struck out five and walked four while taking his second loss.

His next start is scheduled for Tuesday against the Mets. In his lone start against New York last season, Kershaw allowed three runs (one earned) over seven innings in a win.