Nationals starting pitcher Stephen Strasburg was rocked for eight runs (seven earned) on eight hits in 3 1/3 innings to take the loss against the Diamondbacks on Tuesday.
Strasburg had an extra day of rest for Tuesday's start after leaving his last outing early with a shoulder issue.
"Embarrassed. I let the team down. It sucks," Strasburg said.
Strasburg allowed a two-run double in the first inning and then home runs to Ender Inciarte (solo) in the third inning and Mark Trumbo (three-run shot) in the fourth.
Trumbo's blast ended Strasburg's night.
Strasburg's next turn in the rotation is scheduled for Saturday in San Diego.