The Padres confirmed that pitcher Colin Rea will make his Major League debut on Tuesday, per U-T San Diego.
Rea is 5-4 with a 1.95 ERA in Double-A and Triple-A this season.
Odrisamer Despaigne will be moved to the bullpen to create a spot in the rotation for Rea. Despaigne has started 17 games for the Padres this season and come out of the pen in five games. He's 5-8 with a 5.11 ERA.