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An Eastern Conference battle features the Milwaukee Bucks (5-9) hosting the Chicago Bulls (6-9) on Wednesday night. The Bulls beat the Detroit Pistons 122-112 on Sunday, snapping their two-game losing streak. After starting the season off 1-6, the Bucks have won three of their last four games. On Nov. 18, Milwaukee defeated the Houston Rockets 101-100 after Damian Lillard hit a go-ahead layup in the final seconds of the game. Khris Middleton (ankle) remains out for Milwaukee. Lonzo Ball (wrist) will be sidelined for the Bulls. 

Tip-off from Fiserv Forum in Milwaukee is set for 7:30 p.m. ET. Milwaukee is an 8-point favorite in the latest Bucks vs. Bulls odds via SportsLine consensus, while the over/under for total points scored is 238. Before locking in any Bulls vs. Bucks picks, make sure to check out the NBA predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 5 of the 2024-25 NBA season on a sizzling 109-74 roll on all top-rated NBA picks dating back to last season, returning more than $3,000. Anyone following at sportsbooks and on betting apps has seen huge returns.

Now, the model has simulated Bulls vs. Bucks 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and NBA betting lines for Bucks vs. Bulls:

  • Bulls vs. Bucks spread: Milwaukee -8
  • Bulls vs. Bucks over/under: 238 points
  • Bulls vs. Bucks money line: Milwaukee -339, Chicago +269
  • CHI: 7-8 ATS this season 
  • MIL: 4-9-1 ATS this season 
  • Bulls vs. Bucks picks: See picks at SportsLine
  • Bulls vs. Bucks streaming: FuboTV (Try for free)

Why the Bucks can cover

Forward Giannis Antetokounmpo (knee, probable) is a dominant difference-maker in the frontcourt. Antetokounmpo uses his bruising strength to overpower defenders in the paint and plays relentless defense. The eight-time All-Star is first in the NBA in points (31.4), fourth in rebounds (12.4) and eighth in field percentage (60.1%). He has 12 double-doubles this season. In his last outing, Antetokounmpo had 20 points, 13 rebounds and three blocks.

Lillard has the ability to score from all three levels. Lillard owns a reliable jumper and finishes in traffic with ease. The eight-time All-Star is 12th in the league in points (25.3) and assists (6.9). He's scored at least 30 points five times this season. On Nov. 7 versus the Jazz, he finished 34 points, seven assists and four threes. See who to back at SportsLine.

Why the Bulls can cover

Guard Zach LaVine is an athletic ball handler who creates his own shot from any spot on the floor. The 29-year-old logs a team-high 21.3 points, 5.3 rebounds and 4.1 assists per game. He's scored at least 25 points in three of his last five matchups. In the win over the Pistons on Monday, LaVine dropped 25 points, six rebounds, five assists and shot 7-of-14 from downtown.

Center Nikola Vucevic provides Chicago with a playmaker in the frontcourt. Vucevic will be active on the glass and has a soft touch around the rim. He leads the team in rebounds (9.9) with 20.7 points per game. He's also ninth in the NBA in field-goal percentage (59%). In his last outing, Vucevic tallied 29 points and 12 rebounds. This was his 10th double-double of the season. See who to back at SportsLine.

How to make Bulls vs. Bucks picks

SportsLine's model is leaning Under the total, projecting 235 combined points. The model also says one side of the spread is the better value. You can head to SportsLine to see the model's picks

So who wins Bulls vs. Bucks on Wednesday, and which side of the spread is the better value? Visit SportsLine now to see which side of the Bulls vs. Bucks spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.