Lakers vs. Celtics odds, prediction, line, time: 2025 NBA picks for December 5 from proven model
SportsLine's model simulated Los Angeles Clippers vs. Los Angeles Lakers 10,000 times and revealed its top NBA picks today
The Los Angeles Lakers head to the East Coast to take on the Boston Celtics in one of the earliest tips on the Friday NBA schedule. The Lakers (16-5) beat the Raptors on Friday, though LeBron James did break his streak of 1,297 straight games of scoring double figures. The Celtics (13-9) have won three straight, including blowing the Wizards out by 45 points on Friday. The teams haven't revealed their injury reports yet, though Luka Doncic (personal) missed Thursday's game.
Tipoff from TD Garden is set for 7 p.m. ET. The Celtics are 6.5-point favorites in the latest Celtics vs. Lakers odds, while the over/under is 225.5. Before making Lakers vs. Celtics picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.
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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight seasons. The model enters Week 7 of the 2025-26 NBA season on a sizzling 29-14 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.
Now, the model has simulated Lakers vs. Celtics 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and NBA betting lines for Celtics vs. Lakers:
Lakers vs. Celtics spread: | Celtics -6.5 |
Lakers vs. Celtics over/under: | 225.5 points |
Lakers vs. Celtics money line: | Celtics -251, Lakers +205 |
Lakers vs. Celtics picks: | |
Lakers vs. Celtics streaming: | Fubo (Try for free) |
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How to make Lakers vs. Celtics picks
SportsLine's model has simulated Lakers vs. Celtics 10,000 times and is leaning Over the total, projecting 234 combined points.
The model also says one side of the spread hits over 60% of the time. You can head to SportsLine to see that pick.
So who wins Lakers vs. Celtics, and which side of the spread hits over 60% of the time? Visit SportsLine now to see which side of the spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.
