The Cincinnati Bengals will return from their bye week and host the Pittsburgh Steelers in an AFC North showdown on Sunday during the Week 13 NFL schedule. Cincinnati has lost three of its last four games, making this a must-win game for the Bengals. They are 2.5-point favorites in the Week 13 NFL odds, one of six Week 13 NFL spreads smaller than a field goal on Sunday. Another close game is expected in Baltimore when the Ravens (-2.5) host the Eagles in a game between Super Bowl contenders. 

The weekend concludes with Sunday Night Football featuring Buffalo (-7) vs. San Francisco and Monday Night Football pitting Denver (-5.5) against Cleveland. Which Week 13 NFL lines should you target with your Week 13 NFL parlay picks and NFL best bets? Before you make any Week 13 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 13 of the 2024 NFL season on an incredible 22-8 betting hot streak on top-rated NFL picks this year. Longer term, it is on a 202-136 roll on top-rated NFL picks that dates back to the 2017 season and a 56-29 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone following at sportsbooks and on betting apps has seen strong returns.

Now, the model has scoured the Week 13 NFL odds and locked in five confident NFL best bets. If you successfully parlay its sports betting picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 13 NFL picks at SportsLine.

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Top Week 13 NFL picks

After simulating every game 10,000 times, the model is high on the Washington Commanders (-5.5, 43.5) to cover against the Tennessee Titans. Tennessee turned heads last week with its shocking win at Houston as an 8-point underdog, but the Titans had failed to cover the spread in their previous six games. They did not score more than 20 points in any of those six outings, so their win over Houston appears to be an outlier. 

Meanwhile, Washington is suddenly in desperation mode after losing its last three games by one possession. The Commanders rank sixth in the NFL in yards per game (370.5) and fifth in points per game (27.8), led by star rookie quarterback Jayden Daniels. The model has Daniels finishing with 260 total yards on Sunday, which is one reason why Washington is covering the spread in 60% of simulations. See which other NFL parlay picks to make here.

How to make Week 13 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including two underdogs that win outright. You can only see the model's Week 13 NFL best bets and NFL parlay at SportsLine.

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What are the model's top Week 13 NFL picks, and which NFL matchups should you target for an epic 25-1 payout? Visit SportsLine now to see the Week 13 NFL best bets from a model on an 202-136 run on top-rated picks, and find out.