49ers inactives: WR Mario Manningham (shoulder), QB Scott Tolzien, WR A.J. Jenkins, RB LaMichael James, S Trenton Robinson, G Joe Looney, NT Ian Williams.
LT Joe Staley will play despite suffering a concussion Sunday against the New York Giants, and RB Brandon Jacobs will make his debut for the 49ers.
Follow 49ers reporter Kyle Bonagura on Twitter @CBS49ers and @KyleBonagura.
