The Los Angeles Chargers are set to host the Tennessee Titans in a Week 10 AFC battle on Sunday at SoFi Stadium. Los Angeles is 5-3 overall and 2-1 at home, while Tennessee is 2-6 overall and 1-3 on the road. In their first year under Jim Harbaugh the Chargers are 5-2-1 against the spread. Los Angeles is coming off a dominant 27-10 win over the Cleveland Browns in Week 9. The Titans are looking to build some momentum in the second half of the season after getting off to a 1-6 start. Tennessee is coming off a 20-17 overtime win over the New England Patriots in Week 9. Quarterback Will Levis (shoulder) is off the injury report for Tennessee and expected to start. The Chargers list edge rushers Joey Bosa (hip) and Khalil Mack (groin) as questionable. 

Kickoff in Inglewood, Calif. is scheduled for 4:05 p.m. ET. The Chargers are favored by 7.5 points in the latest Chargers vs. Titans odds, and the over/under is 39 points. Before making any Chargers vs. Titans picks, you'll want to see the NFL predictions and betting advice from the proven computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2024 NFL season on an incredible 14-7 betting hot streak on top-rated NFL picks this year. Longer term, it is on a 195-136 roll on top-rated NFL picks that dates back to the 2017 season and a 49-29 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone following at sportsbooks and on betting apps has seen strong returns.

The model has set its sights on Titans vs. Chargers and just locked in its Week 10 NFL picks and predictions. You can head to SportsLine now to see the model's picks. Here are several NFL betting lines for the Chargers vs. Titans game:

  • Chargers vs. Titans spread: Chargers -7.5
  • Chargers vs. Titans over/under: 39 points
  • Chargers vs. Titans money line: Chargers -358, Titans +285
  • Chargers vs. Titans picks: See picks at SportsLine
  • Chargers vs. Titans streaming: FuboTV (Try for free)

Why the Chargers can cover

The Chargers are headed in fresh off scoring the most points they have all season. They cruised past the Browns with points to spare on Sunday, taking the game 27-10. The win made it back-to-back victories for Los Angeles. The Chargers relied on the efforts of J.K. Dobbins, who rushed for 85 yards and two touchdowns, and Justin Herbert, who threw for 282 yards and two touchdowns. 

The Chargers didn't go easy on the quarterback and picked off three passes before the game was over. It was truly a group effort as Alohi Gilman, Elijah Molden, and Tarheeb Still picked up one apiece. The Chargers have been arguably the top defensive team in the NFL this season. They enter Week 10 leading the NFL in points allowed per game (12.3) and eighth in total yards allowed per game (303.8). See which team to pick here.

Why the Titans can cover

Meanwhile, it may have taken overtime to finish the job, but the Titans ultimately got the result they hoped for on Sunday. They snuck past the Patriots, winning 20-17 in overtime. Tennessee put an end to its three-game losing streak.

The Titans' success was the result of a balanced attack that saw several players step up, but Tony Pollard led the charge by rushing for 128 yards. The dominant performance also gave Pollard a new career-high in total yards (154). Pollard is having a nice bounce-back season in his first year with the Titans and has been one of the team's few bright spots. He enters Week 10 with 622 yards and three touchdowns on 142 carries. See which team to pick here. 

How to make Chargers vs. Titans picks

The model has simulated Chargers vs. Titans 10,000 times and the results are in. The model is leaning Over on the point total, and it also says one side of the spread hits nearly 60% of the time. You can only see the model's pick at SportsLine.

So who wins Titans vs. Chargers on Sunday, and which side of the spread hits nearly 60% of the time? Visit SportsLine right now to see which side of the Chargers vs. Titans spread you should be all over Sunday, all from the model on a 195-136 roll on its top-rated NFL picks, and find out.